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Recent Publications in ACLF

Recent Publications in ACLF

[Treatment strategies for acute-on-chronic liver failure]
Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation
Alterations in Gut Microbiome in Cirrhosis as Assessed by Quantitative Metagenomics: Relationship With Acute-on-Chronic Liver Failure and Prognosis
Pre-acute-on-chronic liver failure in hepatitis B-related patients
PREDICTing acute-on-chronic liver failure in patients with acute decompensation
Tri-typing of hepatitis B-related acute-on-chronic liver failure defined by the World Gastroenterology Organization
A Claims-Based Frailty Risk Score Is Associated With Hospitalization for Acute-on-Chronic Liver Failure: But Is It Frailty?
Uncertainty in the impact of liver support systems in acute-on-chronic liver failure: a systematic review and network meta-analysis
A Stepwise Evaluation of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure to Optimize the Indication for Urgent Liver Transplantation
Higher Waitlist Mortality in Pediatric Acute-on-chronic Liver Failure in the UNOS Database
Global hemostatic status in patients with acute-on-chronic liver failure and septics without underlying liver disease
Patient Frailty Is Independently Associated With the Risk of Hospitalization for Acute-on-Chronic Liver Failure
Inappropriate cessation of nucleos(t)ide analog associated with reduced liver transplant-free survival in patients with HBV-related acute on chronic liver failure
M2-like macrophages exert hepatoprotection in acute-on-chronic liver failure through inhibiting necroptosis-S100A9-necroinflammation axis
Cohort profile: a multicentre prospective validation cohort of the Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study
Recognizing Pediatric Acute-on-chronic Liver Failure: the Need of the Hour
Improved prediction of mortality by combinations of inflammatory markers and standard clinical scores in patients with acute-on-chronic liver failure and acute decompensation
Characteristics of Liver Function in Patients With SARS-CoV-2 and Chronic HBV Coinfection
The role of the model for end-stage liver disease-sodium score and joint models for 90-day mortality prediction in patients with acute-on-chronic liver failure
Renal and brain failure predict mortality of patients with acute-on-chronic liver failure admitted to the intensive care unit
Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: An international registry study
Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report
Impact of metabolic risk factors on the severity and outcome of patients with alcohol-associated acute-on-chronic liver failure
Acute-on-chronic liver failure: a global disease
Hemostatic balance in acute-on-chronic liver failure
Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure
Hemophagocytic Lymphohistiocytosis in the Medical ICU: A Single-Institution Cohort Study on Acute Liver Failure and Mortality
Liver transplantation in acute liver failure due to Hepatitis B. Two clinical cases
Noninvasive assessment of liver fibrosis for predicting acute-on-chronic liver failure in patients with chronic hepatitis B
Predicting 90-day mortality at admission and 7 days post-admission among patients with hepatitis B virus-related acute-on-chronic liver failure
Characteristics and outcome of nosocomial bloodstream infection in patients with acute-on-chronic liver failure
A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators
Point-of-Care Echocardiography and Hemodynamic Monitoring in Cirrhosis and Acute-on-Chronic Liver Failure in the COVID-19 Era
Hyperkalemia influences the outcome of patients with cirrhosis with acute decompensation (AD) and acute-on-chronic liver failure (ACLF)
Association between effective hepatic blood flow and the severity and prognosis of hepatitis B virus-related acute on chronic liver failure
Amino acids in acute-on-chronic liver failure: Another piece of the puzzle?
Role of ammonia in predicting the outcome of patients with acute-on-chronic liver failure
A prognostic score for patients with acute-on-chronic liver failure treated with plasma exchange-centered artificial liver support system
Sequential versus mono double plasma molecular adsorption system in acute-on-chronic liver failures: A propensity-score matched study
Dysregulated Adaptive Immunity Is an Early Event in Liver Cirrhosis Preceding Acute-on-Chronic Liver Failure
Renal and brain failure predict mortality of patients with acute-on-chronic liver failure admitted to the intensive care unit
Omega-3 fatty acid lipid emulsions are safe and effective in reducing endotoxemia and sepsis in acute-on-chronic liver failure: An open-label randomized controlled trial
A non-bioartificial liver support system combined with transplantation in HBV-related acute-on-chronic liver failure
Acute-on-chronic liver failure: update on pathogenesis, therapeutic targets, predictive models, and liver transplantation
Acute-on-chronic liver failure due to infarction of multiple cirrhotic nodules
Definitions for Acute-on-Chronic Liver Failure: In Dubio Pro Reo
The systemic inflammation hypothesis: Towards a new paradigm of acute decompensation and multiorgan failure in cirrhosis
Comparing CLIF-C ACLF, CLIF-C ACLF(lactate), and CLIF-C ACLF-D Prognostic Scores in Acute-on-Chronic Liver Failure Patients by a Single-Center ICU Experience
What role should acute on chronic liver failure play in the liver transplant prioritization? A survey of the US based transplant providers
Therapeutic plasma-exchange improves systemic inflammation and survival in acute-on-chronic liver failure: A propensity-score matched study from AARC
Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States
WGO Guidance for the Care of Patients With COVID-19 and Liver Disease
Peripheral T lymphocytes predict the severity and prognosis in patients with HBV-related acute-on-chronic liver failure
Determinants of mortality in patients with cirrhosis and uncontrolled variceal bleeding
Imbalance Between Soluble and Membrane-Bound CD100 Regulates Monocytes Activity in Hepatitis B Virus-Associated Acute-on-Chronic Liver Failure
IgG, a novel predictor for acute-on-chronic liver failure and survival in patients with decompensated cirrhosis?
Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data
Detoxification of bilirubin and bile acids with intermittent coupled plasmafiltration and adsorption in liver failure (HERCOLE study)
Over 500 Liver Transplants Including More Than 400 Living-Donor Liver Transplants in 2019 at Asan Medical Center
Acute (fulminant) liver failure: a clinical and imaging review
Nonalcoholic Steatohepatitis Is the Most Rapidly Increasing Indication for Liver Transplantation in the United States
Initial experience with high-volume plasma exchange in patients with acute liver failure
Fatal cerebral edema in patients with decompensated cirrhosis: A case series
Risk factors for candidaemia in hospitalized patients with liver cirrhosis: a multicentre case-control-control study
Multiple Cycles of Granulocyte Colony-Stimulating Factor Increase Survival Times of Patients With Decompensated Cirrhosis in a Randomized Trial
Insurance Status But Not Race and Ethnicity Are Associated With Outcomes in a Large Hospitalized Cohort of Patients With Cirrhosis
Liver Transplantation Reverses Hepatic Myelopathy in 2 Children With Hepatitis A Infection
Sustained low-efficiency dialysis with regional citrate anticoagulation for patients with liver impairment in intensive care unit: A single-center experience
MELD-Na Is More Strongly Associated with Risk of Infection and Outcomes Than Other Characteristics of Patients with Cirrhosis
PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF
Liver injury in the era of COVID-19
Evaluation and selection of the liver transplant candidate: updates on a dynamic and evolving process
Orthotopic liver transplantation for patients with end-stage alcohol-related liver disease and severe acute alcohol-related hepatitis: a concise review
Prognostic Significance of End-Stage Liver Diseases, Respiratory Tract Infection, and Chronic Kidney Diseases in Symptomatic Acute Hepatitis E
From off-to on-target: New BRAF-inhibitor-template-derived compounds selectively targeting mitogen activated protein kinase kinase 4 (MKK4)
Transfusion with Cryoprecipitate for Very Low Fibrinogen Levels Does Not Affect Bleeding or Survival in Critically Ill Cirrhosis Patients
Intraoperative hypotension during liver transplant surgery is associated with postoperative acute kidney injury: a historical cohort study
Galectin-9 as a biomarker of disease severity
Role of comorbidities on therapeutic persistence of biological agents in rheumatoid arthritis: results from the RECord-linkage On Rheumatic Disease study on administrative healthcare databases
Presentation and Outcomes of Autoimmune Hepatitis Type 1 and Type 2 in Children: A Single-center Study
Pediatric Liver Disease Patients and Secondary Glycosylation Abnormalities
Expanding Indications of Liver Transplantation in Spain: Consensus Statement and Recommendations by the Spanish Society of Liver Transplantation
Drug-induced liver injury: Asia Pacific Association of Study of Liver consensus guidelines
Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity
Presepsin as a biomarker of inflammation and prognosis in decompensated liver disease
Mortality, Risk Factors and Disparities Associated with Esophageal Variceal Bleeding in Children's Hospitals in the United States
Changes in the epidemiology and management of bacterial infections in cirrhosis
Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF


    • Total cases enrolled = 6838
    • Total centers across Asia = More than 90
    • Total manuscripts = 13
    • Total video conferences conducted = 60
    • Total abstract presented in conference by AARC group = More than 50

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