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Recent Publications in ACLF

Recent Publications in ACLF

Impact of Diabetes, Drug-Induced Liver Injury, and Sepsis on Outcomes in Metabolic Dysfunction Associated Fatty Liver Disease-Related Acute-on-Chronic Liver Failure
https://pubmed.ncbi.nlm.nih.gov/39016385/
Hepatic and extrahepatic metabolic modulation in hbv-related decompensated cirrhosis and acute-on-chronic liver failure
https://pubmed.ncbi.nlm.nih.gov/39312464/
Identification of four novel acute-on-chronic liver failure clusters with distinct clinical trajectories and mortality using machine learning methods
https://pubmed.ncbi.nlm.nih.gov/39310931/
From prognostication to therapeutics: Four key questions to accelerate the development of therapeutics for patients with acute-on-chronic liver failure
https://pubmed.ncbi.nlm.nih.gov/39047977/
Acute-on-chronic liver failure in metabolic dysfunction-associated fatty liver disease patients: a disease multiplier
https://pubmed.ncbi.nlm.nih.gov/39107615/
Effect of midodrine on HVPG in advanced chronic liver disease and acute-on-chronic liver failure-A pilot study
https://pubmed.ncbi.nlm.nih.gov/39045811/
Impact of Diabetes, Drug-Induced Liver Injury, and Sepsis on Outcomes in Metabolic Dysfunction Associated Fatty Liver Disease-Related Acute-on-Chronic Liver Failure
https://pubmed.ncbi.nlm.nih.gov/39016385/
Anthocyanin profiling of genetically diverse pigmented potato (Solanum tuberosum L.) clonal accessions from north-eastern sub-Himalayan plateau of India
https://pubmed.ncbi.nlm.nih.gov/39281522/
Changing Etiological Spectrum of Hepatocellular Carcinoma in India-A Systematic Review and Meta-analysis
 
http://https://pubmed.ncbi.nlm.nih.gov/38559423/
Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients
http://https://pubmed.ncbi.nlm.nih.gov/38461166/
Dynamic analysis of acute deterioration in chronic liver disease patients using modified quick sequential organ failure assessment
http://https://pubmed.ncbi.nlm.nih.gov/38600873/
Identifying the early predictors of non-response to steroids in patients with flare of autoimmune hepatitis causing acute-on-chronic liver failure
https://pubmed.ncbi.nlm.nih.gov/36790652/
Combination of GM CSF and carbapenem is superior to carbapenem monotherapy in difficult-to-treat spontaneous bacterial peritonitis: A randomized controlled trial
https://pubmed.ncbi.nlm.nih.gov/37753014/
Drug Resistance in Osteoarticular Tuberculosis: A Study From an Endemic Zone
https://pubmed.ncbi.nlm.nih.gov/37753014/
Tolerance of standard dose albumin infused over 6 hrs for treatment of spontaneous bacterial peritonitis-A randomized controlled trial
https://pubmed.ncbi.nlm.nih.gov/37422602/
Asia-Pacific association for study of liver guidelines on management of ascites in liver disease
https://pubmed.ncbi.nlm.nih.gov/37237088/
Influence of shunt occlusion on liver volume and functions in hyperammonemic cirrhosis patients having large porto-systemic shunts: a randomized control trial
https://pubmed.ncbi.nlm.nih.gov/36094625/
Low-dose continuous terlipressin infusion is effective and safer than intravenous bolus injections in reducing portal pressure and control of acute variceal bleeding
https://pubmed.ncbi.nlm.nih.gov/36542261/
Tadalafil improves erectile dysfunction and quality of life in men with cirrhosis: a randomized double blind placebo controlled trial
https://pubmed.ncbi.nlm.nih.gov/34775577/
Harmonization of ACLF definitions- The First Step Has Gained Momentum!
http://https://pubmed.ncbi.nlm.nih.gov/39321927/
Acute-on-chronic liver failure: Terminology, mechanisms and management
https://pubmed.ncbi.nlm.nih.gov/36938601/
A new definition for metabolic dysfunction-associated fatty liver disease: An international expert consensus statement
https://pubmed.ncbi.nlm.nih.gov/32278004/
[Treatment strategies for acute-on-chronic liver failure] https://pubmed.ncbi.nlm.nih.gov/31463674/
Clinical features and evolution of bacterial infection-related acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/32781201/
Differential inflammasome activation predisposes to acute-on-chronic liver failure in human and experimental cirrhosis with and without previous decompensation https://pubmed.ncbi.nlm.nih.gov/32241903/
Alterations in Gut Microbiome in Cirrhosis as Assessed by Quantitative Metagenomics: Relationship With Acute-on-Chronic Liver Failure and Prognosis https://pubmed.ncbi.nlm.nih.gov/32941879/
Pre-acute-on-chronic liver failure in hepatitis B-related patients https://pubmed.ncbi.nlm.nih.gov/33279256/
PREDICTing acute-on-chronic liver failure in patients with acute decompensation https://pubmed.ncbi.nlm.nih.gov/33279258/
Tri-typing of hepatitis B-related acute-on-chronic liver failure defined by the World Gastroenterology Organization https://pubmed.ncbi.nlm.nih.gov/32445263/
A Claims-Based Frailty Risk Score Is Associated With Hospitalization for Acute-on-Chronic Liver Failure: But Is It Frailty? https://pubmed.ncbi.nlm.nih.gov/33048425/
Uncertainty in the impact of liver support systems in acute-on-chronic liver failure: a systematic review and network meta-analysis https://pubmed.ncbi.nlm.nih.gov/33462764/
A Stepwise Evaluation of Hepatitis B Virus-Related Acute-on-Chronic Liver Failure to Optimize the Indication for Urgent Liver Transplantation https://pubmed.ncbi.nlm.nih.gov/32140946/
Higher Waitlist Mortality in Pediatric Acute-on-chronic Liver Failure in the UNOS Database https://pubmed.ncbi.nlm.nih.gov/32796428/
Global hemostatic status in patients with acute-on-chronic liver failure and septics without underlying liver disease https://pubmed.ncbi.nlm.nih.gov/33006808/
Patient Frailty Is Independently Associated With the Risk of Hospitalization for Acute-on-Chronic Liver Failure https://pubmed.ncbi.nlm.nih.gov/32946660/
Inappropriate cessation of nucleos(t)ide analog associated with reduced liver transplant-free survival in patients with HBV-related acute on chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33341047/
M2-like macrophages exert hepatoprotection in acute-on-chronic liver failure through inhibiting necroptosis-S100A9-necroinflammation axis https://pubmed.ncbi.nlm.nih.gov/33462187/
Cohort profile: a multicentre prospective validation cohort of the Chinese Acute-on-Chronic Liver Failure (CATCH-LIFE) study https://pubmed.ncbi.nlm.nih.gov/33419900/
Recognizing Pediatric Acute-on-chronic Liver Failure: the Need of the Hour https://pubmed.ncbi.nlm.nih.gov/32910090/
Improved prediction of mortality by combinations of inflammatory markers and standard clinical scores in patients with acute-on-chronic liver failure and acute decompensation https://pubmed.ncbi.nlm.nih.gov/32478437/
Characteristics of Liver Function in Patients With SARS-CoV-2 and Chronic HBV Coinfection https://pubmed.ncbi.nlm.nih.gov/32553907/
The role of the model for end-stage liver disease-sodium score and joint models for 90-day mortality prediction in patients with acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33218737/
Renal and brain failure predict mortality of patients with acute-on-chronic liver failure admitted to the intensive care unit https://pubmed.ncbi.nlm.nih.gov/33346095/
Outcomes following SARS-CoV-2 infection in patients with chronic liver disease: An international registry study https://pubmed.ncbi.nlm.nih.gov/33035628/
Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report https://pubmed.ncbi.nlm.nih.gov/33530924/
Impact of metabolic risk factors on the severity and outcome of patients with alcohol-associated acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/32970356/
Acute-on-chronic liver failure: a global disease https://pubmed.ncbi.nlm.nih.gov/33632711/
Hemostatic balance in acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33650250/
Profiling circulating microRNAs in patients with cirrhosis and acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33665588/
Hemophagocytic Lymphohistiocytosis in the Medical ICU: A Single-Institution Cohort Study on Acute Liver Failure and Mortality https://pubmed.ncbi.nlm.nih.gov/33458685/
Liver transplantation in acute liver failure due to Hepatitis B. Two clinical cases https://pubmed.ncbi.nlm.nih.gov/31623992/
Noninvasive assessment of liver fibrosis for predicting acute-on-chronic liver failure in patients with chronic hepatitis B https://pubmed.ncbi.nlm.nih.gov/33389677/
Predicting 90-day mortality at admission and 7 days post-admission among patients with hepatitis B virus-related acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33484512/
Characteristics and outcome of nosocomial bloodstream infection in patients with acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/32118849/
A dynamic prediction model for prognosis of acute-on-chronic liver failure based on the trend of clinical indicators https://pubmed.ncbi.nlm.nih.gov/33469110/
Point-of-Care Echocardiography and Hemodynamic Monitoring in Cirrhosis and Acute-on-Chronic Liver Failure in the COVID-19 Era https://pubmed.ncbi.nlm.nih.gov/33438491/
Hyperkalemia influences the outcome of patients with cirrhosis with acute decompensation (AD) and acute-on-chronic liver failure (ACLF) https://pubmed.ncbi.nlm.nih.gov/33446445/
Association between effective hepatic blood flow and the severity and prognosis of hepatitis B virus-related acute on chronic liver failure https://pubmed.ncbi.nlm.nih.gov/32282547/
Amino acids in acute-on-chronic liver failure: Another piece of the puzzle? https://pubmed.ncbi.nlm.nih.gov/33622546/
Role of ammonia in predicting the outcome of patients with acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33553393/
A prognostic score for patients with acute-on-chronic liver failure treated with plasma exchange-centered artificial liver support system https://pubmed.ncbi.nlm.nih.gov/33446902/
Sequential versus mono double plasma molecular adsorption system in acute-on-chronic liver failures: A propensity-score matched study https://pubmed.ncbi.nlm.nih.gov/33435806/
Dysregulated Adaptive Immunity Is an Early Event in Liver Cirrhosis Preceding Acute-on-Chronic Liver Failure https://pubmed.ncbi.nlm.nih.gov/33574809/
Renal and brain failure predict mortality of patients with acute-on-chronic liver failure admitted to the intensive care unit https://pubmed.ncbi.nlm.nih.gov/33454389/
Omega-3 fatty acid lipid emulsions are safe and effective in reducing endotoxemia and sepsis in acute-on-chronic liver failure: An open-label randomized controlled trial https://pubmed.ncbi.nlm.nih.gov/33450081/
A non-bioartificial liver support system combined with transplantation in HBV-related acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33536531/
Acute-on-chronic liver failure: update on pathogenesis, therapeutic targets, predictive models, and liver transplantation https://pubmed.ncbi.nlm.nih.gov/33606401/
Acute-on-chronic liver failure due to infarction of multiple cirrhotic nodules https://pubmed.ncbi.nlm.nih.gov/33547858/
Definitions for Acute-on-Chronic Liver Failure: In Dubio Pro Reo https://pubmed.ncbi.nlm.nih.gov/33560654/
The systemic inflammation hypothesis: Towards a new paradigm of acute decompensation and multiorgan failure in cirrhosis https://pubmed.ncbi.nlm.nih.gov/33301825/
Comparing CLIF-C ACLF, CLIF-C ACLF(lactate), and CLIF-C ACLF-D Prognostic Scores in Acute-on-Chronic Liver Failure Patients by a Single-Center ICU Experience https://pubmed.ncbi.nlm.nih.gov/33572927/
What role should acute on chronic liver failure play in the liver transplant prioritization? A survey of the US based transplant providers https://pubmed.ncbi.nlm.nih.gov/32772464/
Therapeutic plasma-exchange improves systemic inflammation and survival in acute-on-chronic liver failure: A propensity-score matched study from AARC https://pubmed.ncbi.nlm.nih.gov/33529450/
Characteristics and Outcomes of Individuals With Pre-existing Kidney Disease and COVID-19 Admitted to Intensive Care Units in the United States https://pubmed.ncbi.nlm.nih.gov/32961244/
WGO Guidance for the Care of Patients With COVID-19 and Liver Disease https://pubmed.ncbi.nlm.nih.gov/33230011/
Peripheral T lymphocytes predict the severity and prognosis in patients with HBV-related acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/33592861/
Determinants of mortality in patients with cirrhosis and uncontrolled variceal bleeding https://pubmed.ncbi.nlm.nih.gov/32561318/
Imbalance Between Soluble and Membrane-Bound CD100 Regulates Monocytes Activity in Hepatitis B Virus-Associated Acute-on-Chronic Liver Failure https://pubmed.ncbi.nlm.nih.gov/33646067/
IgG, a novel predictor for acute-on-chronic liver failure and survival in patients with decompensated cirrhosis? https://pubmed.ncbi.nlm.nih.gov/33548386/
Effects of Early Placement of Transjugular Portosystemic Shunts in Patients With High-Risk Acute Variceal Bleeding: a Meta-analysis of Individual Patient Data https://pubmed.ncbi.nlm.nih.gov/32980344/
Detoxification of bilirubin and bile acids with intermittent coupled plasmafiltration and adsorption in liver failure (HERCOLE study) https://pubmed.ncbi.nlm.nih.gov/32710265/
Over 500 Liver Transplants Including More Than 400 Living-Donor Liver Transplants in 2019 at Asan Medical Center https://pubmed.ncbi.nlm.nih.gov/33010937/
Acute (fulminant) liver failure: a clinical and imaging review https://pubmed.ncbi.nlm.nih.gov/33635361/
Nonalcoholic Steatohepatitis Is the Most Rapidly Increasing Indication for Liver Transplantation in the United States https://pubmed.ncbi.nlm.nih.gov/32531342/
Initial experience with high-volume plasma exchange in patients with acute liver failure https://pubmed.ncbi.nlm.nih.gov/33400840/
Fatal cerebral edema in patients with decompensated cirrhosis: A case series https://pubmed.ncbi.nlm.nih.gov/33157306/
Risk factors for candidaemia in hospitalized patients with liver cirrhosis: a multicentre case-control-control study https://pubmed.ncbi.nlm.nih.gov/32360775/
Multiple Cycles of Granulocyte Colony-Stimulating Factor Increase Survival Times of Patients With Decompensated Cirrhosis in a Randomized Trial https://pubmed.ncbi.nlm.nih.gov/32088302/
Insurance Status But Not Race and Ethnicity Are Associated With Outcomes in a Large Hospitalized Cohort of Patients With Cirrhosis https://pubmed.ncbi.nlm.nih.gov/32389884/
Liver Transplantation Reverses Hepatic Myelopathy in 2 Children With Hepatitis A Infection https://pubmed.ncbi.nlm.nih.gov/33490305/
Sustained low-efficiency dialysis with regional citrate anticoagulation for patients with liver impairment in intensive care unit: A single-center experience https://pubmed.ncbi.nlm.nih.gov/32511862/
MELD-Na Is More Strongly Associated with Risk of Infection and Outcomes Than Other Characteristics of Patients with Cirrhosis https://pubmed.ncbi.nlm.nih.gov/32100160/
PBMC transcriptomics identifies immune-metabolism disorder during the development of HBV-ACLF https://pubmed.ncbi.nlm.nih.gov/33431576/
Liver injury in the era of COVID-19 https://pubmed.ncbi.nlm.nih.gov/33584070/
Evaluation and selection of the liver transplant candidate: updates on a dynamic and evolving process https://pubmed.ncbi.nlm.nih.gov/33278150/
Orthotopic liver transplantation for patients with end-stage alcohol-related liver disease and severe acute alcohol-related hepatitis: a concise review https://pubmed.ncbi.nlm.nih.gov/33433074/
Prognostic Significance of End-Stage Liver Diseases, Respiratory Tract Infection, and Chronic Kidney Diseases in Symptomatic Acute Hepatitis E https://pubmed.ncbi.nlm.nih.gov/33520734/
From off-to on-target: New BRAF-inhibitor-template-derived compounds selectively targeting mitogen activated protein kinase kinase 4 (MKK4) https://pubmed.ncbi.nlm.nih.gov/33199152/
Transfusion with Cryoprecipitate for Very Low Fibrinogen Levels Does Not Affect Bleeding or Survival in Critically Ill Cirrhosis Patients https://pubmed.ncbi.nlm.nih.gov/33450778/
Intraoperative hypotension during liver transplant surgery is associated with postoperative acute kidney injury: a historical cohort study https://pubmed.ncbi.nlm.nih.gov/33430770/
Galectin-9 as a biomarker of disease severity https://pubmed.ncbi.nlm.nih.gov/33494007/
Role of comorbidities on therapeutic persistence of biological agents in rheumatoid arthritis: results from the RECord-linkage On Rheumatic Disease study on administrative healthcare databases https://pubmed.ncbi.nlm.nih.gov/33660559/
Presentation and Outcomes of Autoimmune Hepatitis Type 1 and Type 2 in Children: A Single-center Study https://pubmed.ncbi.nlm.nih.gov/32796427/
Pediatric Liver Disease Patients and Secondary Glycosylation Abnormalities https://pubmed.ncbi.nlm.nih.gov/33520896/
Expanding Indications of Liver Transplantation in Spain: Consensus Statement and Recommendations by the Spanish Society of Liver Transplantation https://pubmed.ncbi.nlm.nih.gov/32345868/
Drug-induced liver injury: Asia Pacific Association of Study of Liver consensus guidelines https://pubmed.ncbi.nlm.nih.gov/33641080/
Translation of IRF-1 Restricts Hepatic Interleukin-7 Production to Types I and II Interferons: Implications for Hepatic Immunity https://pubmed.ncbi.nlm.nih.gov/33584648/
Presepsin as a biomarker of inflammation and prognosis in decompensated liver disease https://pubmed.ncbi.nlm.nih.gov/33484772/
Mortality, Risk Factors and Disparities Associated with Esophageal Variceal Bleeding in Children's Hospitals in the United States https://pubmed.ncbi.nlm.nih.gov/33450222/
Changes in the epidemiology and management of bacterial infections in cirrhosis https://pubmed.ncbi.nlm.nih.gov/33504138/
Characterization of Blood Immune Cells in Patients With Decompensated Cirrhosis Including ACLF https://pubmed.ncbi.nlm.nih.gov/33613548/
Preventing Small-for-size Syndrome in Living Donor Liver Transplantation: Guidelines From the ILTS-iLDLT-LTSI Consensus Conference https://pubmed.ncbi.nlm.nih.gov/36790652/
Soluble factors and suppressive monocytes can predict early development of sepsis in acute-on-chronic liver failure https://pubmed.ncbi.nlm.nih.gov/35502507/
Prevalence of and Factors Associated with Sleep-Wake Abnormalities in Patients with Cirrhosis https://pubmed.ncbi.nlm.nih.gov/34276152/
Establishment of a murine model of acute-on-chronic liver failure with multi-organ dysfunction https://pubmed.ncbi.nlm.nih.gov/34435344/

ACHIEVEMENTS

    • Total cases enrolled = 10809
    • Total centers across Asia = More than 95
    • Total manuscripts = More than 40
    • Total video conferences conducted = 102
    • Total abstract presented in conference by AARC group = More than 50

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